Boiling them would work, but then you'd just have gross water instead of useless pills. Heat is the answer. I've dropped a bottle of pills next to a space heater in a benzo stupor (do not recommend), and the bottle was turning black and smelled awful. The pills definitely were not as effective as they were before. Hormones may be different in terms of heat requirements, but I'm sure if you did it to all of her pills it would mess things up.
If you do this though you're kind of really mean and awful.