Author Topic: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals  (Read 1529 times)

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Offline splooge gook

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #15 on: October 26, 2014, 02:23:21 pm »
what do you think about 'psychedelic' animals?

I think the chemical (typically DMT or related) acts to scare the shit out of a more developed predator that eats it and become convinced the toad or whatever might have some bizarre combat ability lol.
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Offline splooge gook

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #16 on: October 26, 2014, 02:27:26 pm »
Hydration, by oxymercuation, of 3-methyl-1-butene gives 3-methyl-2-butanol.
What is the observed rotation of this product, using a 20% solution in ethanol in a 1dm polarimeter cell?.
Assume the specific roatation of the pure (S)-enantiomer to be +16ยบ

Adding water + oxidized mercury-ation of the chemical gives the next chemical
They want to know what the chemical in a cell with some ethanol will rotate to, or whether they will become S/R enaniometers

so R-entaiomer -16 and S = +16 = total rotation of 32 degrees?

i'm guessing. i said neurochemistry,not chemistry. mostly pharmacology and how it relates to the brain.
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"I've shot meth before, is it water soluble?" -semiazas
"I fapped so much and talked to Semiazas. I was addicted from that point forward." - DARE

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Offline constantinople

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #17 on: October 26, 2014, 02:30:42 pm »
:facepalm:
Not Istanbul.

Offline splooge gook

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #18 on: October 26, 2014, 02:34:06 pm »
neurochemistry = role chemicals play in receptors, channels, cells, etcetcetc; not the actual construction of chemicals, faggot
Everything I post iz fiction

"I've shot meth before, is it water soluble?" -semiazas
"I fapped so much and talked to Semiazas. I was addicted from that point forward." - DARE

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Offline Teessider

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #19 on: October 26, 2014, 02:35:35 pm »
Your thread States ask me questions on chemicals. Isn't chemistry done with chemicals?

Offline splooge gook

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #20 on: October 26, 2014, 02:36:16 pm »
oh wait i did say chemicals. i was stoned when i wrote the title. my bad. by chemicals i  basically meant drugz
Everything I post iz fiction

"I've shot meth before, is it water soluble?" -semiazas
"I fapped so much and talked to Semiazas. I was addicted from that point forward." - DARE

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Offline equanimity

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #21 on: October 26, 2014, 03:11:39 pm »
Why trileptal and remeron over other medications?


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Offline xbcnfujv

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #22 on: October 26, 2014, 03:20:05 pm »
how i make teh GOOD meth?

Offline splooge gook

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #23 on: October 26, 2014, 03:27:29 pm »
well you said "in your opinion", and i've went through a variety of psychiatric meds and most of them didn't work.

SSRIs/SNRIs/whatever all basically target the same systems in your brain no matter which chemical they are, mirtizapine is a derivative of mianserin which either is or may be a tetracyclic antidepressant. mirtizapine is a "new and improved" version of mianserin because it's less likely to cause sides effects. it is also a good sleep aid/anxiety reducer/and genuinely just makes me feel happier without the total emotional numbing of SSRIs. Mirtizapine is a nonadrenergic and specific serotenergic antagonist, making it more "unique" then most SSRIs. If SSRIs don't work for you, try SNRIs, if SNRIs don't work, try mirtizapine or trazadone or a MAOI or whatever the fuck else. if you're lucky you'll finally find a medication that works for you, but for it to happen it's good to know about how the antidepressants each either basically mimic each other or bind to random receptors in a way that turns out to reduce depression.

lithium, valproate, topamax, etc, can totally rape your body to pieces if you're not careful,well ive read topamax just makes you kind of retarded. oxcarbazepine has almost no side effects beside a mild drunk euphoric feeling and some double vision (i take it with my xanax while syncanning), but otherwise has no noticeable effects besides a decrease in aggression/irritability/manic meth rants that is very noticeable after a few weeks of treatment. i'm sure there are other, more FDA-approved and promoted mood stabilizers though.
Everything I post iz fiction

"I've shot meth before, is it water soluble?" -semiazas
"I fapped so much and talked to Semiazas. I was addicted from that point forward." - DARE

https://www.zoklet.net/bbs/showthread.php?t=276946 (use internet wayback)

Offline splooge gook

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #24 on: October 26, 2014, 03:28:51 pm »
how i make teh GOOD meth?

accumulate psuedophederine over time.

1. do panny's shake and bake

2. download the pdf "Official Guide To Methamphetamine Manufacture" it's a real book but too lazy to google the precise name
Everything I post iz fiction

"I've shot meth before, is it water soluble?" -semiazas
"I fapped so much and talked to Semiazas. I was addicted from that point forward." - DARE

https://www.zoklet.net/bbs/showthread.php?t=276946 (use internet wayback)

Offline xbcnfujv

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #25 on: October 26, 2014, 03:39:59 pm »
that's a shitty answer -- i want my money back.

Offline equanimity

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #26 on: October 26, 2014, 03:53:26 pm »
Probably off topic, but is it ever okay for a person to commit suicide?  If so, under which circumstances?


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Offline John Smith

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Re: ask me anythingz: neurochemistry/psychology/psychometrics/drugz/chemicals
« Reply #27 on: October 28, 2014, 10:05:02 pm »
Sploo, do you think there is, or could feasibly be, something you could combine with psychedelics, mainly LSD DMT psilocybin/psilocin mescaline, that could greatly reduce the chance of, strength of, or even eliminate the chance of a bad trip without interfering with the psychedelic? I'm sure you know that benzos generally abort trip, unless taken at very low doses, but even then it changes the character in a direction I don't want: http://www.shroomery.org/forums/showflat.php/Number/542674/fpart/1/vc/1

Do you think d-cycloserine could help?: http://en.wikipedia.org/wiki/Cycloserine#Implications_in_fear_conditioning.2C_memory_consolidation.2C_and_extinction

There are only a few reports with phenibut, one stated that lower doses seemed to have the intended positive effect, but higher ones might reduce the intensity.

Here's an interesting anecdote:
Quote
Back many years ago when I was still experimenting with various nootropics/supplements and psychs(mostly aya) I've tried a small, barely thresh-hold amount of aya under above average effects of phenibut(somewhat euphoric and relaxed) and I couldn't believe how fast and how hard to was hitting me, I had to abort. The closed eyed visuals came on within half an hour and were very different, with classical fantasy creatures like fairies and fancy dressed wizards pointing to a deep well in the ground telling me its time to explore. I wish I proceeded with the experience however It wasn't the right time since it was mid-day and flatmates were present.

This is a possibility:
http://en.wikipedia.org/wiki/Pinazepam
http://www.ncbi.nlm.nih.gov/pubmed/6147192

Quote
These findings indicate that pinazepam is a pure anxiolytic agent devoid of hypnotic effect or motor disorders, characteristics that make it a useful drug for daytime use.

In particularly I'm interested in this, which I've brought up before, but it doesn't seem to be available anywhere:
http://en.wikipedia.org/wiki/Imidazenil

Quote
Imidazenil is a GABAA partial agonist[2] with an unusual profile of effects, producing some of the effects associated with normal benzodiazepines such as anticonvulsant and anxiolytic effects, yet without any notable sedative[3] or amnestic[4] effects. In fact, imidazenil blocks the sedative effects of diazepam, yet without lowering the convulsion threshold,[5] and so potentially could be a more flexible antidote than the antagonist flumazenil which is commonly used to treat benzodiazepine overdose at present.

This unusual profile of effects makes imidazenil potentially a very useful drug. In animal studies it has been shown to be an effective anxiolytic and strong anticonvulsant, yet without many of the side effects associated with other benzodiazepines; it does not produce tolerance[6] or dependence,[7] reverses the amnestic effects of conventional benzodiazepines, and does not potentiate the effects of alcohol.[8][9]

I know about the effects of inhibitory effects of GABA on neurotransmission, but for people with (far) below optimal levels this probably won't be as significant an issue, and that large norepinephrine and adrenaline releases can be a positive part of an experience, provide a feeling of exhilaration and energy. I'd like to experiment with it, if only I could my hands on imidazenil. Phenibut doesn't seem to have much of an effect on me, and I tried 3 or 4 grams without tolerance, with a boost later on. May have given me withdrawals the day after, though.

Also, what psychedelics have you done? I didn't even smoke weed until I was 23 and was an absolute undeveloped mess even at 18 when living with my parents and dealt with them invading my privacy, so I'm certainly not disparaging you. Have you thought about growing shrooms? It's incredibly easy to accomplish and hide, as long as you aren't a complete fucking idiot like most people apparently are, thinking it's as easy as planting a seed and requires no significant reading. DMT extraction would make you way cool.
« Last Edit: October 28, 2014, 10:52:39 pm by John Smith »